Air Service MSP is Delta Air Lines’ second largest hub, base for Sun Country, and an operations site for nearly every major domestic carrier and a growing number of international airlines. In 2017, airlines offered non-stop service to nearly 160 destinations from MSP: 131 domestic and 28 international. Multiple airlines served 58 of those routes – a record for MSP – helping keep fares competitive. Alaska, Delta, Frontier, KLM, Southwest, Spirit and Sun Country airlines launched a total of 16 new routes from MSP in 2017. Added airline routes included: KLM launched scheduled service to MSP in March 2017, the first time the airline has served the Twin Cities since 2001. The airline offers three roundtrips a week between Amsterdam and MSP. In October 2017, KLM became the first airline to offer MSP travelers service on the new Boeing 787 Dreamliner. That same month, JetBlue Airways announced it will launch service at MSP in May 2018, with three daily roundtrip flights between MSP and Boston. 16 17 Amsterdam Aruba (two airlines) Austin Cincinnati Cleveland Fort Myers Marquette Nashville New Orleans San Francisco San Diego Santa Rosa/Sonoma Sault Ste. Marie Tampa Tucson